Bin Chen, PhD
Principal Investigator, Associate Professor (CV)
Dept. of Pediatrics and Human Development
Dept. of Pharmacology and Toxicology
Dept. of Computer Science and Engineering (adjunct)
Dept. of Epidemiology and Biostatistics (adjunct)
Dept. of Medicine (adjunct)
Bin was recruited to MSU through the Global Impact Initiative. Prior to this position, Bin was a faculty member (instructor, assistant professor) at UCSF for three years. Bin trained as a chemist in college, worked as a software engineer before graduate school, trained as a chem/bioinformatician in graduate school, worked as a computational scientist at Novartis, Pfizer and Merck. He received his PhD in informatics at Indiana University, Bloomington and pursued his postdoctoral training in Dr. Atul Butte's lab at Stanford University. Bin co-founded DahShu, a non-profit organization to promote research and education in data sciences. As a PI, he has received >$7 million research funding. He has also contributed to a number of big grants (e.g., P01 and U24) as a co-investigator. During weekends, Bin plays soccer or coaches kids to play soccer.
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Rama Shankar, PhD
Postdoctoral Scholar (2018-), K99/R00 Awardee
Rama completed his MS in Biotechnology from the University of Hyderabad, India, in 2010, and his PhD in Computational Biology from Jawaharlal Nehru University, India, in 2018. He joined the Chen lab in 2018. He is interested in applying single-cell transcriptomics to identify novel biomarkers.
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Dimitri Joseph, MS
DO/PhD student (2020-)
Dimitri is a DO/PhD candidate pursuing a graduate degree in Pharmacology and Toxicology. He received his MSc in Biochemistry and Cell Biology from Stony Brook University. He is interested in leveraging bioinformatics to understand health disparities and immunology.
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Ruoqiao Chen, BS
BMS PhD student (2021-)
Ruoqiao received her BS in Medical Science from Huazhong University of Science & Technology in China. Her current research focuses on developing machine learning models to predict surface protein expression and developing foundation models for drug discovery.
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Dmitry Leshchiner, MD
Postdoctoral scholar (2022-)
Dmitry Leshchiner received his MD from I.M. Sechenov First Moscow State Medical University and then spent a couple of years at Harvard Medical School as a research associate before pursuing postdoctoral training at Boston College in 2020. In 2022, he joined the Chen lab and Horibata lab. He is interested in utilizing computational tools to discover novel therapeutics.
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Xiaodan Zhang, MS
Data Science Specialist (2022-)
Xiaodan received her MS in Statistics from the University of South Florida and had over 10 years of teaching experience before joining the Chen lab to lead the EHR projects.
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Nabasmita Talukdar, MS
PhD student in Biostats (2022-)
Nabas received her MS in Statistics from Delhi University in India. She is interested in using real-world data to discover better therapeutics.
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Shubham Koirala, BS
PhD student in Genetics and Genome Sciences (2024-)
Shubham received his BS in Biotechnology from Kathmandu University, Nepal. He is interested in leveraging machine learning and large-scale transcriptomics to discover new biomarkers for pediatric cancers.
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Zolt Palmer, BS
PhD student in Biochemistry and Molecular Biology (2025-)
Zolt received his BS from GVSU. He is interested in systems-based drug discovery.
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Linqing Mo
PhD student in Computer Science (2024-), co-advised with Prof. Jiayu Zhou
Linqing received his BS in Chemistry from the University of Science and Technology of China and his MS in both Chemistry and Data Science from Michigan State University. He is interested in representation learning in drug discovery.
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Lingxiao Li, MS
PhD student in CS (2024-), advised by Prof. Jiayu Zhou
Lingxiao received his MS in Computer Science from Boston University. He closely collaborates with the lab on multimodal generative AI for drug discovery.
EmailWe always welcome highly motivated trainees to join the lab. For postdoc candidates, please send your CV and research interests to Dr. Chen. For graduate students, depending on your interests and backgrounds, please apply through the BioMolecular Science program, the Genetics and Genome Sciences Program, the Biostatistics program, or the Computer Science Program. Feel free to approach Dr. Chen if you plan to apply. Chen lab has the tradition to host high-school summer interns every year. Please contact Dr. Chen before April if you are interested. We occasionally recruit undergraduate and medical students. For all the trainees, before the application, please ensure you have some experience with programming (R and Python are preferred) and statistics. The Resource page will direct you to some great sources to learn programming and statistics.
Alumni
| Shreya Paithankar | Lab assistant, 2018-2025 | Applying PHD |
| Sardar Mehtab Bin Murtaza | CS/Chemistry undergraduate 2023-2024 | CS PhD student at UC Merced |
| Aakash Dave | CHM Medical Student, 2023-2024 | Medical Student at CHM, MSU |
| Han Meng | CS MS student, 2021-2024 | CS PhD student at William & Mary |
| Jing Xing | Postdoc, 2018-2022 | Young PI at Shanghai Institute of Materia Medica, Chinese Academy of Sciences |
| Jeremy Haskins | Part-time technician, 2020-2022 | Senior Scientist at Altay Therapeutics |
| Mengying Sun | CS PhD student, 2019-2022, co-advised by Prof. Jiayu Zhou | Data Scientist, Facebook(Meta) |
| Ke Liu | Postdoc, 2017-2021, Research Assistant Professor 2021-2022 | Assistant Professor, Qilu Scholar, Shandong University |
| Eugene Chekalin | Postdoc, 2019-2021 | Senior computational biologist at Illumina |
| Austin VanVelsen | Medical student, 2020-2021 | Medical student at CHM, MSU |
| Tyler VanVelsen | Medical student, 2020-2021 | Medical student at CHM, MSU |
| Jeanne Yang | Summer intern, 2021 | Undergraduate at UM |
| Shan-Ju Yeh | Visiting Scholar, 2019-2020 | PhD student and then professor at Taiwan National Tsinghua University |
| Christopher Chang | Capstone student, 2019-2020 | Medical student at COM |
| Krista Young | Capstone, 2019-2020 | Medical student at COM |
| Xiangyu Chen | High-school summer intern, 2020 | East Grand Rapids High School, admitted to UPenn |
| Yingying Wu | Postdoc, 2019 | Postdoc at Harvard, then AP at University of Houston |
| Rae Felismino | Capstone student, 2019 | Medical student at COM |
| Cathy Lee | Capstone student, 2019 | Medical student at COM |
| Suchir Gupta | High-school summer intern, 2019 | Grand Rapids Central High School, then admitted to UM |
| Billy Zeng | UCSF medical student, 2017-2019 | UCSF medical student |
| Albert Jiao | Medical student, 2018 | Matched Radiology at Harvard |
| Kasim Fassia | Medical student, 2018 | Medical student at MSU |
| Patrick Newbury, MD | Postdoc, 2018-2019 | Radiation oncology resident at University of Oklahoma |
| Anthony Sciarini | Intern from GVSU, 2018 summer and fall | GVSU undergraduate |
| Keith Schmitt | Intern from GVSU, 2018 summer and fall | GVSU undergraduate |
| Anita Wen | Summer intern from UC Davis, 2018 | UC Davis |
| Before we moved to MSU in 2018 | ||
| Jordan Spatz | Medical student | UCSF |
| Michael F. Sharpnack | Medical student, volunteer | Ohio State University |
| Reuben Sarwal | Summary Intern | Undergraduate, UC Berkeley |
| Tanisha Joshi | Summary Intern | High school |
| Jane Wei | Summary Intern | Undergraduate, Cornell University |
| Rachel (Menghua) Wu | Summary Intern | High school, accepted into MIT |
| Charles Pei | Summary Intern | High school, accepted into Harvard, co-mentored by Marina Sirota |